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Is breast cancer inherited?

This is one of a series of articles answering questions in this POST: 108 Most Asked Questions For Drugstore Marketing Activities

Most women who get breast cancer do not have any family history of breast cancer. Just because a family member had breast cancer does not always mean that you will get breast cancer.

We do know that there are some genes associated with a known increased risk of breast cancer. These are BRCA 1 (breast cancer 1, early onset human tumor suppressor gene) and BRCA 2 (breast cancer type 2, susceptibility protein). Only 10 percent of women with breast cancer have these inherited genes. These women usually get breast cancer at a young age and have multiple family members with breast or ovarian cancer.

—-By Answered by Stephanie Valente, DO. 

Breast cancer is a disease in which certain cells in the breast become abnormal and multiply uncontrollably to form a tumor. Although breast cancer is much more common in women, this form of cancer can also develop in men. In both women and men, the most common form of breast cancer begins in cells lining the milk ducts (ductal cancer). In women, cancer can also develop in the glands that produce milk (lobular cancer). Most men have little or no lobular tissue, so lobular cancer in men is very rare.

In its early stages, breast cancer usually does not cause pain and may exhibit no noticeable symptoms. As the cancer progresses, signs and symptoms can include a lump or thickening in or near the breast; a change in the size or shape of the breast; nipple discharge, tenderness, or retraction (turning inward); and skin irritation, dimpling, redness, or scaliness. However, these changes can occur as part of many different conditions. Having one or more of these symptoms does not mean that a person definitely has breast cancer.

In some cases, cancerous tumors can invade surrounding tissue and spread to other parts of the body. If breast cancer spreads, cancerous cells most often appear in the bones, liver, lungs, or brain. Tumors that begin at one site and then spread to other areas of the body are called metastatic cancers.

A small percentage of all breast cancers cluster in families. These cancers are described as hereditary and are associated with inherited gene mutations. Hereditary breast cancers tend to develop earlier in life than noninherited (sporadic) cases, and new (primary) tumors are more likely to develop in both breasts.

—-By NIH.GOV

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