58-14-0 ,Pyrimethamine ,active API chemical, Pharmaceutical level, supplier from China, buy now

Description

This is a pharmaceutical level API chemical. Supplying from China. Please talk to us before purchasing to confirm stock and delivery time. Thank you.

2,4-diamino-5-(p-chlorophenyl)-6-ethylpyrimidine
5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diyldiamine
5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine

Pyrimethamine is a synthetic derivative of ethyl-pyrimidine with potent antimalarial properties. Pyrimethamine is a competitive inhibitor of dihydrofolate reductase (DHFR). DHFR is a key enzyme in the redox cycle for production of tetrahydrofolate, a cofactor that is required for the synthesis of DNA and proteins. This agent is often used in combination with other antimalarials for the treatment of uncomplicated falciparum malaria. (NCI04)